Hi Maquenzie,
In Little Reader and Little Math, you can choose to "lock" your keyboard, so this way even if your baby bangs on the keyboard the lessons won't be affected (note that when your keyboard is locked only the ESC key is usable, as this is how you stop the lesson presentation).
Similarly you can also lock your mouse, should you prefer to use your keyboard. If you want to lock both your mouse and keyboard during the lesson, you can just set your lesson to play on "auto forward" so you don't need to press anything (the auto forward feature can be further customized in case you want it slower or faster).
Hope this helps